Biomarkers and molecular diagnosis of gastrointestinal and pancreatic neoplasms
نویسندگان
چکیده
منابع مشابه
[Diagnosis and treatment of pancreatic cystic neoplasms].
Diagnosing Pancreatic Cysts Doctors use computed tomography (CT) or magnetic resonance imaging(MRI)scanstodiagnosepancreaticcystsanddeterminetheir type. These tests can also identify features of the cysts that suggest an increased risk of cancer. If imaging scans cannot identify the typeof cyst or if the cyst has aconcerningappearance,doctorsmayalsouseanendoscopicultrasound procedure. This invo...
متن کاملSurgical and molecular pathology of pancreatic neoplasms
BACKGROUND Histologic characteristics have proven to be very useful for classifying different types of tumors of the pancreas. As a result, the major tumor types in the pancreas have long been classified based on their microscopic appearance. MAIN BODY Recent advances in whole exome sequencing, gene expression profiling, and knowledge of tumorigenic pathways have deepened our understanding of...
متن کاملDiagnosis and therapy of neuroendocrine neoplasms of the gastrointestinal tract
A neuroendocrine neoplasm (nen) is a tumor that originates in neuroendocrine cells capable of producing peptides or amines. neuroendocrine neoplasms of the digestive system are also referred to as gastroenteropancreatic neuroendocrine neoplasms (GeP nen) and constitute a heterogeneous group of growths originating from at least 15 types of specialized cells spread throughout the stomach, small i...
متن کاملThe role of molecular analysis in the diagnosis and surveillance of pancreatic cystic neoplasms.
CONTEXT Molecular analysis of pancreatic cyst fluid obtained by EUS-FNA may increase diagnostic accuracy. We evaluated the utility of cyst-fluid molecular analysis, including mutational analysis of K-ras, loss of heterozygosity (LOH) at tumor suppressor loci, and DNA content in the diagnoses and surveillance of pancreatic cysts. METHODS We retrospectively reviewed the Columbia University Panc...
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ژورنال
عنوان ژورنال: Nature Reviews Gastroenterology & Hepatology
سال: 2010
ISSN: 1759-5045,1759-5053
DOI: 10.1038/nrgastro.2010.153